New Tool in Gene Therapy Arsenal

Researchers at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts have discovered a new way to transfer DNA, thus safely protecting cells from retinal degeneration. A peptide called PEG-POD is the vehicle for therapeutic gene delivery. “We think the level of gene expression seen with PEG-POD may be enough to protect the retina from degeneration, slowing the progression of eye disorders, and we have preliminary evidence that this is indeed the case,” said Siobhan Cashman PhD, research assistant professor in the department of ophthalmology at TUSM.

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