A pseudovitelliform detachment occurs when the macula detaches from the pigment epithelial layer as a result of an abnormal accumulation of fluid in the subretinal space. This type of retinal detachment may occur in individuals with adult onset vitelliform macular dystrophy or other advanced forms of retinal disease.

When the macular area of the retina detaches, straight-ahead vision is drastically affected. Central vision may be suddenly blurred. It may be difficult to read; lines of words may appear wavy, or portions may disappear.

Retinal detachments require surgery. Left untreated, the retina can detach completely and can cause blindness. However, there are several surgical options for retinal detachments, and all are highly successful. Laser photocoagulation is used to seal off tears or holes. Surgical procedures to re-attach the retina include scleral buckling, vitrectomy, and pneumatic retinopexy. It is important to know that even after the retina is successfully re-attached, vision may not be perfectly restored. This is especially true when the macular area of the retina was affected.